Blar i NTNU Open på forfatter "Bjørås, Karine Øian"

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    • Alkyladenine DNA glycosylase associates with transcription elongation to coordinate DNA repair with gene expression 

      Montaldo, Nicola Pietro; Bordin, Diana Lilian; Brambilla, Alessandro; Rösinger, Marcel; Martin, Sarah Fordyce; Bjørås, Karine Øian; Bradamante, Stefano; Aas, Per Arne; Furrer, Antonia; Olsen, Lene Christin; Kunath, Nicolas; Otterlei, Marit; Sætrom, Pål; Bjørås, Magnar; Samson, Leona D.; van Loon, Barbara (Journal article; Peer reviewed, 2019)
      Base excision repair (BER) initiated by alkyladenine DNA glycosylase (AAG) is essential for removal of aberrantly methylated DNA bases. Genome instability and accumulation of aberrant bases accompany multiple diseases, ...

    • Diverse functions of DNA glycosylases processing oxidative base lesions in brain 

      Scheffler, Katja; Bjørås, Karine Øian; Bjørås, Magnar (Peer reviewed; Journal article, 2019)
      Endogenous and exogenous oxidative agents continuously damage genomic DNA, with the brain being particularly vulnerable. Thus, preserving genomic integrity is key for brain health and neuronal function. Accumulation of DNA ...

    • Dynamics of base excision repair proteins; recruitment to replication forks and DNA lesions 

      Bjørås, Karine Øian (Doctoral theses at NTNU;2017:275, Doctoral thesis, 2017)
      DNA er arvestoffet vårt og finnes i de fleste celler i kroppen. DNA er satt sammen av to tråder bestående av sukkermolekyler, fosfat og nitrogenbaser (nukleotider). Disse kjemiske strukturene blir kontinuerlig utsatt for ...